If not, you can manually activate the control surface in Live's Preferences → Link MIDI. Choose the required control surface (Komplete Kontrol A, or Komplete Kontrol S Mk 2), then select your keyboard's input and output ports. Launch Live and the keyboard should be automatically activated and ready for use.Ĥ. Connect your Komplete Kontrol keyboard.ģ. 269.00 4 Interest Free Payments of 67. Note: You have to install the latest version of Komplete Kontrol even if you don't use the plug-in, otherwise the control surface won't work with Live.Ģ. Micro-size keyboard controller with 32 keys for all your virtual instruments and effects Affordable entry point into the NI world Synth-action, custom NI. NATIVE INSTRUMENTS KOMPLETE KONTROL M32 32-NOTE MICRO-SIZED USB CONTROLLER KEYBOARD WITH SOFTWARE BUNDLE MA32. Install the very latest version of Komplete Kontrol using the Native Access app. Here are detailed instructions for Komplete Kontrol Setup on the NI Knowledge Base. Native Instruments Komplete Kontrol M32 VGB03 Digital Portable Keyboard (32 Keys). How to enable Komplete Kontrol support in Liveġ. In this tutorial, you'll learn how to register your Komplete Kontrol M32, sign up for Komplete Now, get your copy of Ableton Live Lite, and install instruments and effects with Native. Setting up a Native Instruments Komplete Kontrol keyboardĪs of version 10.0.5, we have included control surface support for the Native Instruments Komplete Kontrol A-Series keyboards, and as of 10.1, Komplete Kontrol S Mk2 and M32 keyboards.
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Although the addition of chemotherapy did not prolong OS (HR, 0.88), the combined strategy led to significant benefits compared to the immunotherapy-only approach with respect to PFS (7.7 vs. Patients were allocated to either durvalumab plus tremelimumab followed by durvalumab maintenance (n = 150) or the same regimen plus platinum doublet chemotherapy followed by durvalumab alone or combined with pemetrexed, depending on histology (n = 151). Indeed, approval in the USA has been granted by the Food and Drug Administration in May 2020.Īnother trial to assess the combined first-line approach of dual checkpoint inhibition and chemotherapy in stage IV NSCLC is the international, randomized phase II CCTG BR.34 study. Overall, the CheckMate 9LA study demonstrated that NI plus a limited course of chemotherapy should be considered as a new first-line treatment option for patients with advanced NSCLC. Immune-related AEs were mostly grades 1 and 2. The combination did not induce any new AEs any-grade treatment-related AEs mainly included nausea, anemia, asthenia, and diarrhea. Patients fared better regarding survival with the immunotherapy-based approach regardless of histology (squamous vs. The OS advantage increased over time according to updated results obtained after a follow-up of 12.7 months, median OS was 15.6 vs. OS was defined as the primary endpoint.Īfter a minimum follow-up of 8.1 months, CheckMate 9LA met its primary endpoint at the time of the pre-planned interim OS analysis, with a statistically significant benefit for the immunotherapy-based regimen compared to chemotherapy only (14.1 vs. In the control arm (n = 358), four cycles of chemotherapy were administered, followed by optional pemetrexed maintenance in patients with non-squamous tumors. Among 719 patients with stage-IV or recurrent NSCLC, 361 received NI combined with two cycles of chemotherapy. The phase III, randomized CheckMate 9LA trial was conducted based on the assumption that adding a limited course of chemotherapy to first-line NI might provide rapid disease control while building on the durable OS benefit observed with NI in CheckMate 227. Two cycles of chemotherapy plus checkpoint blockade: CheckMate 9LA In May 2020, the regimen has received approval in the USA in this indication, while the European application was withdrawn four months earlier. The authors concluded that NI is a novel chemotherapy-sparing first-line treatment option for patients with advanced NSCLC. Treatment-related select AEs of NI affecting the skin, gastrointestinal tract, endocrine system and other areas decreased over time. The extended safety follow-up over at least 36.3 months did not reveal any new signals for the combination. Similar results were observed for the group with PD-L1 < 1 % (82 % vs. This showed that among patients with PD-L1 ≥ 1 %, 70 % of those achieving complete or partial responses at six months with NI were alive at three years in the chemotherapy arm, this applied only to 39 %. Also, the combination showed lasting superiority over both nivolumab monotherapy and nivolumab plus chemotherapy independent of PD-L1 expression.Īn exploratory landmark analysis assessed the impact of response at six months on long-term OS. More than one third of all responders remained in response after three years with NI (38 % and 34 % for PD-L1 expressors ≥ 1 % and < 1 %, respectively), while the respective rates in the chemotherapy group ranged below 5 %. 22 % with the combination and chemotherapy, respectively (HR, 0.79). In Part 1a, 3-year OS rates were 33 % vs. Patients in Part 1a showed PD-L1 expression ≥ 1 %, while those in Part 1b tested PD-L1–negative (< 1 %).Īt three years, first-line NI continued to provide long-term benefits compared to chemotherapy regardless of PD-L1 expression. chemotherapy (n = 186) and nivolumab plus chemotherapy (n = 177). Part 1 consisted of Part 1a that compared NI (n = 396) with chemotherapy (n = 397) and nivolumab monotherapy (n = 396), as well as Part 1b which assessed NI (n = 187) vs. presented the updated 3-year efficacy and safety results from Part 1 of the trial. First-line nivolumab plus ipilimumab (NI) was shown to significantly prolong OS compared to chemotherapy in patients with advanced NSCLC irrespective of tumor PD-L1 expression in the randomized, phase III CheckMate 227 study. The most ideal approach is to wire the camera system to the rear lights so the camera view automatically triggers when your truck goes reverse. The mounting bracket opens a lot of installation possibilities. The PDF manual can be accessed from that page as well. The official Garmin BC 20 Wireless Backup Camera product page on Garmin’s website provides five videos that clearly demonstrate how to install this camera. You just need a drill and a 0.36-inch drill bit along with a standard #2 Philips screwdriver along with screws, cable ties or bolts to keep the transmitter in place and a solderless wire-splice connector. With the Garmin BC 20, it is best to consult a professional too but Garmin has a passion for support and offers a way for do-it-yourself fans to independently install the entire system. Many of the backup cameras in the market are unbranded or come from a not-so-known manufacturer so support is questionable and your best bet is to have a professional install the system. Easy to read 7 display, Customized RV routing¹ for lower 48 states and Canada, America’s RV Parks & Services directory, RV trip planning and sharing, Lifetime map² and traffic³ updates, Wireless backup camera compatible. One of the main features of this wireless backup camera is Garmin’s branding. GARMIN RV 760LMT with BC 20 - for sale, best price - 429.95 - Includes BC 20 Wireless backup camera. The Garmin BC 20 Wireless Backup Camera is an example of a product that can give old trucks that modern car functionality. On top of that, larger vehicles like trucks don’t have that at all. Fortunately, not everyone has the money to buy these advanced automobiles and that is why Garmin’s products continue to sell. Even though Garmin continues to churn out high-quality navigation products, not all consumers are aware of that and probably won’t be curious since they can just use the built-in features of their new car. Cars are pretty advanced in software nowadays where you can use the touchscreen to for navigation or entertainment services. These cameras work together with the screens that are built into the control console of the car’s interior. This is why many of the midrange and high-end models of consumer cars are having backup cameras and/or sensors built right into the back of the car. When backing your car, there is always that possibility of something getting in the way and you just can’t see it. Reversing a car is easy for the experienced driver but no matter how good and experienced you are, you still have to deal with the blind zone problem. Please note: editable files are required for processing in production. The following word processor file formats are acceptable for the main manuscript document:
Heart-Seeking Bow: increased Attack and Special damage reduced Attack and Special recovery time. Stygian Blade (Zagreus Aspect): now increases move speed and Attack speed (rather than Dash distance).Stygian Blade: adjusted Dash-Strike recovery and input buffering.You may receive a large surplus of Darkness, as a refund from adjusted Mirror of Night costs for Fated Authority and Fated Persuasion.
There usually is more to it than just the addition of cellulase enzyme. P&G once included cellulase in all Tide detergents (containers had that Cotton registered trademark), but now it seems they pick and choose.īy chewing up bobbles thus making cotton textiles smoother the working theory is laundry will be softer as well. Main difference between Tide with Downy "Free" and regular Tide "Free and Gentle" is the former contains cellulase enzymes, but not the latter IIRC. Those oils or waxes will make them slippery. Again usually silicone and is why directions on container warn about getting the stuff on floors or surfaces. If the starch in question used in bath has any sort of oil or wax yes, it will cut suds to some extent.Īll spray starches and sizing also have some sort of lubricant for reasons given above. In theory laundry that is going to be starched by hand or machine should be well rinsed and free of soap or detergent residue. Modern starches for some time now use silicone or some other lubricant that won't stain fabrics, but also will wash out at next laundering. If something wasn't put into starch, or even if it was the irons themselves were waxed with some substance for same reasons. This was no small feat back in days when an "iron" was just that, a big heavy piece of cast iron. Object was to provide some sort of oil or wax substance that would allow iron to glide freely across fabric. Butter, lard, candle wax, spermaceti, etc. Going back to days when starches were first used as routine part of laundering all sorts of things were added to make ironing easier. You probably are not going to buy gap insurance or a major mechanical protection extended warranty from Signal Financial FCU, nor complete a $10,000 auto loan re-fi or a $2,500+ balance transfer (especially since the 2.5% fee on the balance transfer is a minimum of $62.50-making it only worthwhile if you would’ve done a balance transfer at 3% anyway and just need another 6 months of 0% APR). Realistically, this is a $100 bonus that can be up to $150 if you satisfy the direct deposit requirement. There is an early account termination fee of $25 if a Savings, Checking, or Money Market account is closed within 6 months of account opening. The way this is stated, it should apply equally to the Standard Money Market account in the Signal Connect Bundle (which you do not get a bonus for) and the Premium eMoney Market Account in the Signal Premium Bundle (which you do get a bonus for). There is a separate $10 monthly maintenance fee for money market accounts unless a $2,500 minimum average daily balance is maintained. Maintain a combined $25,000 average monthly balance in share accounts (excluding share certificates) and conduct 5 signature-based debit card transactions per month OR have a mortgage with a starting balance of $250,000 or greater to avoid the $25 monthly maintenance fee. Maintain a $250 average monthly balance in your checking account or conduct 5 signature-based debit card transactions per month to avoid the $10 monthly maintenance fee. Avoiding FeesĪ full schedule of fees is located on this page and in this PDF. The normal yearly fee for WABA is $35, but it sounds like you can join WABA and Signal Financial FCU at the same time and they will pay for your membership for the first year. On the application page, it is possible to select “I would like to become a member through WABA” and proceed with the application. You are an employee of a business member of the Wheaton-Kensington Chamber of Commerce.(Signal will pay the first year’s membership fee for new members!). You are a member of the Washington Area Bicyclist Association (WABA).View a complete list of Select Employee Groups here. You are a current employee, retiree, or surviving spouse within one of our Select Employee Groups (including Verizon, Verizon Wireless, AT&T and over 200 others).You are a close relative (living in the same household or not) of a current Signal member.You live, work, attend school, or worship in Washington, DC, or in Prince George’s County, MD inside the Beltway.You can join Signal Financial FCU if you satisfy any of the following requirements: Bonus credits are reportable for tax purposes (i.e.An aggregate bonus will be paid as a deposit into the member’s share savings account, within 45 days of the bonus requirements being met.Only one $50 bonus can be earned for each product, and multiples of any products will not result in additional bonuses.To receive the Visa balance transfer bonus, the member must complete a Visa balance transfer, including any applicable balance transfer fee.To be eligible for the Vehicle Loan bonus, the loan payments must be made using automatic transfer from the member’s Signal Financial FCU account to pay the vehicle loan.To receive the bonus for the debit card, the member must swipe the card at a merchant at least 12 times a month during the 6 month promotional period.To qualify for the Direct Deposit bonus, Direct Deposit amount must be deposited at least once a month for the amount of $750.00 or greater for a period of at least 4 consecutive months during the 6 month qualification time frame.However, members can purchase other products to satisfy the bundle requirements. Members who purchased ancillary services (Gap and MMP) from the dealer are excluded from direct purchases of GAP and MMP from Signal Financial FCU. The GAP and MMP products must be purchased directly through Signal Financial FCU.In order to remain eligible, the account must be in good standing at the time of the bonus credit.In order to be eligible for the $50 bonus credit within each applicable bundle category, the account must be enrolled in a bundle account program for 6 consecutive months, to be shown on the statement during the 7th month.Current Signal members may participate by selecting an applicable bundle package. Cash bonus shall not to exceed $350 for Signal Connect members and $400 for Signal Premium members.$50 for High-Rate Money Market (Signal Premium Product Bundle only).$50 for Debit Card (usage of 12x/month).$50 for Visa Balance Transfer ($2,500 min.).Earn up to $400 when you open a Signal Premium Product Bundle or up to $350 when you open a Signal Connect Product Bundle for the following activities:. As a result, Acorns recommends that clients ensure their financial condition, risk tolerance and investment goals are kept current in their investor profile on the Acorns App.Īs clients make further deposits into, or withdrawals from, their Acorns Accounts, the corresponding transactions made by Acorns are designed to rebalance the account toward the target allocation of the relevant Portfolio. Acorns reviews and evaluates portfolio allocation determinations periodically in line with material updates to a client’s investor profile. A client can choose to override such algorithmic determination by selecting a different portfolio. You will not be permitted to invest in both types of portfolios at the same time.Īcorns uses a proprietary computer software-based algorithm to match each client’s Acorns Account(s) to the portfolio best suited to the client’s investment goals, based on a client’s investor profile questionnaire, which incorporates the client’s financial situation, investment horizon, and risk profile, among other factors. Upon opening an account, you will be prompted to select whether you wish to invest in an ESG Portfolio or Core Portfolio. The ESG Portfolios are distinguished from Core Portfolios by specifically focusing on investing in ETFs that hold companies with strong MSCI ESG records. Acorns currently offers five (5) model portfolios reflecting investment outlooks and risk tolerances ranging from ‘conservative’ to ‘aggressive’ in the “Core Portfolio” and four (4) model portfolios in the “Environmental, Social and (Corporate) Governance (“ESG”) Portfolio” (there is no “conservative” portfolio available in the ESG Portfolios). The ETFs within the model portfolios are managed by independent third-party Investment Advisers. Acorns’ model portfolios reflect target asset allocations across various asset classes, for example stocks (equities) and bonds (fixed income). The primary service Acorns provides to investors is investment advice through model portfolios comprised of Exchange Traded Funds (“ETFs”). UGMA/UTMA investment accounts for the benefit of minors (“Acorns Early Account”).Individual Retirement Accounts, often referred to as “IRAs” (“Acorns Later Account”), and.Traditional individual investment accounts (“Acorns Invest Account”).As part of such services we offer you the ability to invest in the following three main types of investment accounts (“Acorns Account(s)”): What investment services and advice can you provide me?Īcorns only offers investment services and advice to retail investors. Free and simple tools are available to research firms and financial professionals at /CRS, which also provides educational materials about Broker Dealers, Investment Advisers, and investing. This relationship summary is designed to provide you with a summary of the services that can be offered to you by Acorns Advisers and Acorns Securities, the fees charged for such services and various other information, such as the conflicts of interest affecting Acorns and its personnel and any relevant legal or disciplinary history. We refer to Acorns Advisers and Acorns Securities collectively below as “Acorns.” Acorns Advisers and Acorns Securities are subsidiaries of Acorns Grow Incorporated (“Acorns Grow”). Acorns Securities is also a member of the Securities Investor Protection Corporation (“SIPC”). Acorns Advisers, LLC (“Acorns Advisers”) is registered as an Investment Adviser with the Securities and Exchange Commission (“SEC”) and, its affiliate, Acorns Securities, LLC (“Acorns Securities”), is registered as a Broker Dealer with the SEC and is a member of the Financial Industry Regulatory Authority, Inc.(“FINRA”). 357 SIG achieved some early success after being adopted by several state-level law enforcement agencies, who later reported that the cartridge performed well in the field. It featured a bottleneck design, characterized by a straight-walled case with no shoulder this type of design hadn’t been seen on a semi-automatic handgun cartridge since the early 1960s. The cartridge’s design also had some unique characteristics. 357 Magnum cartridge, which would make it more powerful than 9mm and. 357 SIG cartridge was designed to have similar ballistics to the. 357 SIG cartridge was patterned in part after its predecessors- It had a similar case length as 10mm and a bullet diameter equivalent to 9mm. 40 S&W continued to grow in popularity leading into the mid-90s, leading firearm manufacturers Sig Sauer and Federal formed a joint partnership to develop their own all-new semi-automatic cartridge.357 SIG debuted in 1994 and it was hoped by its developers to be an even better alternative to 9mm than. 40 S&W gain respect among commercial gun buyers.357 SIG Attempts to Overtake. Many law enforcement agencies signed contracts with Glock to produce. By 1990, the new wave of lightweight polymer pistols had begun to take a foothold on the firearms market, with Glock leading the way. 40 S&W cartridge’s early success was due to its adoption by Glock. The cartridge had close to identical dimensions to the 10mm, but with a shorter case and overall cartridge length, making it small enough to fit into the medium-frame of 9mm handguns. 40 S&W cartridge debuted on January 17, 1990, and began to gain traction among both law enforcement agencies and civilian gun buyers almost immediately. The FBI likely knew that 10mm wouldn’t be an effective long term solution, and for this reason they put in a request with Smith & Wesson to develop a brand new cartridge, one with similar ballistics of 10mm, but with more manageable recoil.40 S&W Enters Into Market While 10mm did pack significantly greater stopping power than any other semi-auto cartridge at that time, it came with numerous drawbacks, chief among them being the relatively massive recoil it generated. This was a fairly new load, first developed in 1984, and prior to the FBI’s adoption hadn’t been used by any law enforcement agency. With this in mind, the FBI began to conduct ballistics testing to potentially find a new official sidearm caliber.45 ACP was thought to be the likely replacement caliber at the onset of testing, but ultimately the FBI elected to go with the 10mm Auto cartridge. The primary concern was that the round simply didn’t have enough stopping power. 38 Special revolvers with 9mm at this point, but in the aftermath of the shootout the efficacy of 9mm was being brought into question. William Russell Matix and Michael Platt were both hit multiple times during the shootout, but were able to continue fighting, killing 2 agents and wounding another 5 before being downed. 38 Special revolvers and 9mm pistols, almost lost a gunfight to two serial bank robbers. As some of you might remember, 1986 was the year the infamous Miami FBI shootout took place, wherein 8 FBI agents, armed with six-shot. 357 SIG came to be, we need to go back to the year 1986. 9mm Falls Out of Favor With US Law Enforcement This will give us a clearer picture on how each of these calibers came to be, as well as provide insight into their rise and fall in popularity. We’ll be going into detail on the differences between these two calibers, but before we do that I want to cover some background information on what was happening during the late 80’s up until present day. In this comparison guide we will be taking a look at two such calibers. And it was also a time where several new cartridges were given their chance among law enforcement agencies in the US to potentially replace cartridges like 9mm. It was a time denoted by several advancements in ballistics technology, which helped shaped popular cartridges like 9mm into what they are today. The 1990s was a fascinating of period of time in firearms history. In October 2022, Britney Spears took a hiatus from Instagram after using her posts to publicly call out her family. ALSO READ| Britney Spears clarifies after deleting Instagram account, says she is celebrating engagement with Sam Asghari Despite her past deactivations, she had reactivated her account within a few days. In mid-November, she declined to join Sam Asghari on an Instagram Live session, stating that she did not wish to engage with them at the time. However, in January, she clarified that the reason behind her decision was the mockery she faced over her dance videos, expressing the need for a break from the platform. Prior to deactivating her account, she had posted several affectionate messages about her family members. In December 2022, Britney Spears unexpectedly deleted her Instagram account, leaving her fans puzzled. This recent deactivation raises questions about Britney's control over her social media, as she had previously deactivated her Instagram account several times. In contrast, Asghari celebrated the occasion by sharing affectionate posts, referring to Britney as his "better half" and sharing a compilation of their wedding day on June 9, 2022, calling her “the woman of my dreams.” Britney Spears deactivated her Instagram account Asghari celebrated the occasion by sharing affectionate posts, referring to Britney as his "better half". While her Instagram has disappeared, her Twitter account remains active. This marks the eighth time the 41-year-old singer has deleted her account within a span of one year. Britney Spears has once again made the decision to deactivate her Instagram account, and interestingly, this coincides with her approaching first wedding anniversary alongside her husband Sam Asghar. |
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